Process development

Conventional manufacturing uses batch processing with laboratory testing conducted on collected samples to evaluate quality. It is an approach which has been successful in providing quality products to the public. However, today significant opportunities exist for improving chemical development, manufacturing, and quality assurance through innovation in product and process development, process analysis, and process control. The chemical industry generally has been hesitant to introduce innovative systems into the manufacturing sector for a number of reasons, not least of which is the perception that the existing regulatory system is rigid and unfavorable to the introduction of innovative systems. 

It is evident that chemical manufacturing will need to employ innovation, cutting edge scientific and engineering knowledge, along with the best principles of quality management to respond to the challenges of new discoveries (e.g., novel drugs and nanotechnology) and ways of doing business (e.g., individualized therapy, genetically tailored treatment). It is anticipated that regulatory policies will be more reluctant to rise to this challenge.

MACOE have experience with a wide range of manufacturing processes across a wide range of industries and can assist in implementing process changes and improvements.

On Innovation.

Manufacturers of liquid health, personal care and pharmaceutical products require a high degree of flexibility in both the production and filling/packing of the products. They seek; reduced capital cost; reduced (hygienic) space requirement; minimized downtime associated with change over of liquids during production; minimized product loss. To solve this problem GEA Liquid Processing have developed and delivered a technical solution leading to a significant improvement in the manufacturing of liquid blends. The result being a flexible and cost-effective in-line blending system that feature precise measuring technology, materials-handling technology and control systems. The in-line blending units are delivered as skid mounted ready for operation systems which can be installed right in front of the product filling line. Only the direct supply of raw materials such as active pharmaceutical ingredients (API's), flavors, and base material to the "unit" is required for the start of the production.